How It All Started
Our story began at a psychedelic facilitator licensing course, where two very different journeys crossed paths.
Dr. Lynn Puana came from a traditional medical background. For years she prescribed medications by the book, only to watch some of those very treatments—like opioids—fuel the addiction crisis and harm the very people she wanted to help. That realization lit a fire in her: to search for better ways forward, beyond the limits of “traditional” medicine. Her research led her to natural medicines like peptides and psilocybin, therapies long respected by indigenous cultures and now proven by modern science.
Amir Mahmoud’s path was different but deeply connected. With a decade of frontline healthcare experience in trauma, critical care, and psychiatry, Amir saw how patients often slipped through the cracks of a system focused on quick fixes. His training in neuroscience, psychiatry, and integrative approaches gave him tools to look deeper—into the body, brain, and subconscious patterns driving suffering.
When we met, we realized our visions aligned: to build a place where patients receive the best of both worlds—clinical expertise and natural healing, science and spirit, tradition and innovation.
That place is now the Premier Integrative & Cognitive Medical Institute. A sanctuary where ketamine, psilocybin, peptides, neurocognitive biofeedback, red light, and other advanced therapies are not “alternatives”—they are part of a carefully guided, evidence-based system of healing designed to help you reclaim your life.
Our Practitioners
Lynn Welch Puana, MD
Founder & Medical Director, Premier Integrative & Cognitive Medical Institute
Lynn Welch Puana, MD is the Founder and Medical Director of the Premier Integrative & Cognitive Medical Institute. After more than two decades treating patients with chronic pain, trauma, addiction, and complex medical needs, she became deeply committed to transforming how we approach brain and mental wellness. Her passion for this work grew from both her clinical experience and her father’s missed Parkinson’s diagnosis, which was only recognized after he had already progressed to end stage Alzheimer’s—long past the time when early detection could have changed his outcome.
This experience shaped her core belief: we must care for the brain proactively, with the same commitment we give to heart disease or cancer prevention. She advocates for establishing a baseline of brain health early in adulthood and monitoring it over time—allowing patients to catch changes early, get answers sooner, and preserve the best version of themselves.
Driven by both science and compassion, Dr. Puana designed PICMI around the most advanced diagnostic tools available today, including genomic testing, functional brain mapping, and cellular medicine evaluations. Her goal is to help patients understand, through clear scientific evidence, why they think, feel, and function the way they do—so they can finally begin healing in a real and meaningful way.
Through integrative therapies, cellular medicine, and state-regulated psychedelic-assisted treatments, PICMI offers patients a personalized path toward emotional balance, cognitive strength, and true mental wellness. Dr. Puana’s mission is simple: to care for the whole person, to bring clarity where there has been confusion, and to help every patient build a healthier, stronger, more hopeful version of themselves.
Amir Mahmoud, NP, PMHNP-BC
Clinical Director | Psychiatric-Mental Health Nurse Practitioner
Amir Mahmoud is a board-certified Psychiatric-Mental Health Nurse Practitioner with advanced training in neuroscience-based psychiatry, integrative medicine, and innovative approaches to mental health care. He holds dual bachelor’s degrees in Psychology and Criminal Justice, along with a Master of Science in Nursing and a Master of Business Administration—reflecting both clinical expertise and healthcare leadership.
With over a decade of diverse healthcare experience spanning emergency services, critical care, trauma systems, and psychiatric medicine, Amir brings a comprehensive perspective to patient care. He evaluates and treats children, adolescents, and adults for conditions including depression, anxiety, ADHD, trauma-related disorders, and mood imbalances. His background in high-acuity settings allows him to recognize complex presentations and coordinate care across specialties, ensuring patients receive safe, effective, and integrated treatment.
Amir blends evidence-based psychiatry with leading-edge neuroscience and integrative therapies. His approach combines medication management, cognitive and behavioral therapies, and mindfulness-based strategies with innovative modalities such as ketamine-assisted therapy, neuromodulation, and peptide-supported mental health optimization. When appropriate, he incorporates emerging technologies—including brain mapping and guided virtual reality meditation—to deepen neuroplasticity and accelerate healing. Known for balancing science with empathy, Amir empowers patients to build resilience, clarity, and sustainable well-being.
Amir is passionate about innovation, clinical excellence, and creating transformative pathways for healing at the intersection of psychiatry, neuroscience, and integrative medicine.
Limited Time Promotion
For a limited time, get a comprehensive EEG brain scan for $49. This safe, non-invasive assessment provides insight into brain function, with results reviewed by trained professionals. Appointments are limited—get on the waiting list today.