Ketamine Therapy in Denver

Treat the Root Cause, Not Just the Symptoms.Try Ketamine Therapy.

Our physician-directed ketamine therapy program combines personalized evaluation, medically supervised treatment, therapeutic support, and integration to help you move toward lasting emotional wellness.

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Complimentary|No Obligation
  • Board-Certified Physicians
  • Evidence-Based Approach
  • Personalized Treatment Plans

Your brain is unique. Your treatment should be too.

Thoughtful, physician-guided care tailored to how your brain and body respond.

What is Ketamine-Assisted Therapy?

Ketamine-assisted therapy is a physician-guided treatment approach that combines ketamine therapy with preparation, clinical support, and integration. Ketamine may create a temporary window of increased mental flexibility, helping some patients approach difficult thoughts and emotions from a different perspective. With careful screening, medical supervision, and personalized support, the goal is to turn those treatment experiences into meaningful, lasting progress.

How Ketamine-Assisted
Therapy Works

  • Consultation & Evaluation - Review your symptoms, treatment history, health, and medications to determine if ketamine therapy is appropriate.

  • Preparation - Learn what to expect, discuss your goals, and prepare for your treatment sessions.

  • Ketamine Treatment - Receive physician-supervised treatment in a comfortable clinical environment with your safety monitored throughout.

  • Integration & Continued Care - Process insights with your care team, monitor progress, and support long-term mental wellness.

A patient checking in to Premier Cognitive

Why Ketamine?

  • Fast-Acting Potential

    Unlike many traditional medications, ketamine may begin working much sooner for some patients.

  • Supports New Perspectives

    Temporary increases in mental flexibility may help patients approach difficult thoughts and emotions differently.

  • Comprehensive Clinical Care

    Treatment is delivered with physician oversight, therapeutic support, and individualized planning.

  • Long-Term Change

    Ongoing integration and follow-up care help translate treatment experiences into sustainable improvements.

Is Ketamine Therapy Right For You?

  • Depression continues despite treatment
  • Anxiety interferes with daily life
  • Trauma symptoms remain unresolved
  • You've tried medications with limited success
  • You're seeking physician-supervised innovative care
Schedule a FREE Consultation
A patient getting a consultation from a doctor

Our Ketamine Programs

Ketamine Therapy Options Designed Around Your Needs.

Group Experience

Price: $2,499

A supportive, community-based experience. We hold sessions the first of every month.

  • Screening
  • 2 Preparation Sessions
  • 1 Ketamine Session
  • IV Hydration
  • 2 Integration Sessions
  • Care Coordination

Best for: Community & Connection

FREE Consult

Individual Experience

Price: $4,799

A private, one-on-one experience fully tailored to you.

  • Screening
  • 2 Preparation Sessions
  • 1 Ketamine Session
  • IV Hydration
  • 2 Integration Sessions
  • Care Coordination

Best for: Privacy & Personalized Care

FREE Consult

Premier Signature Neuroplasticity Intensive

Price: Starting at $14,999

Our most comprehensive physician-directed brain health program, combining neurofeedback, psychedelic therapies, precision medicine, and personalized care into one fully integrated experience.

There is no one-size-fits-all protocol. Your physician will build a personalized treatment plan based on your individual needs and goals. The services below are examples of therapies that may be incorporated into your program; some may not be recommended for you, while other treatments or services may be added as appropriate.

Your personalized treatment plan may include:

  • Neurofeedback Therapy Treatment Course
  • One-on-One Physician-Directed Care
  • Multiple Brain Maps & Progress Reviews
  • Advanced Bloodwork & DNA Testing
  • Personalized Supplement Protocol
  • Psilocybin-Assisted Therapy (frequency individualized)
  • Ketamine-Assisted Therapy (frequency individualized)
  • IV Hydration
  • Care Coordination
  • Multiple Provider Visits & Integration Sessions

Best for: Patients seeking the highest level of personalized care through a comprehensive program designed to optimize brain health and support lasting change.

FREE Consult

Not sure which program is right for you? Let's find the best path for your goals. Schedule a free consultation.

Hear from Our Patients

Real experiences. Real perspectives.
Hear directly from patients about their experiences with our team, treatments, and approach to care.

Watch Their Stories

Frequently Asked Questions

  • Is ketamine-assisted therapy legal in Denver and Colorado?
    Yes. Ketamine therapy is legal and can be provided by qualified medical professionals in a clinical setting. Our program is delivered with appropriate medical oversight and individualized care.
  • What conditions can ketamine-assisted therapy help with?
    Ketamine-assisted therapy is commonly used to support treatment-resistant depression and may also be considered for anxiety, PTSD, OCD, and other persistent mental health symptoms.
  • How is ketamine administered?
    At our clinic, ketamine is administered in a calm, comfortable clinical setting under physician supervision. Your treatment approach is determined based on your individual needs, and your response is monitored throughout each session.
  • How does ketamine affect the brain?
    Ketamine works differently from traditional antidepressants by acting primarily on the brain's glutamate system, including NMDA receptors involved in neural communication. This can temporarily increase communication between brain cells and support a period of greater neuroplasticity. During this time, patients may experience shifts in perception and emotional processing that can complement therapeutic work and support new ways of responding to challenging thoughts or patterns.
  • Is ketamine therapy safe, and what are the potential side effects?
    Ketamine can cause temporary effects such as dissociation, dizziness, nausea, sleepiness, changes in perception, anxiety, and increases in blood pressure or heart rate. We screen for potential risks before treatment and provide medical supervision throughout each session. Most side effects occur during or shortly after treatment and resolve as the effects wear off.
  • Can ketamine therapy become addictive?
    Ketamine is a controlled substance with potential for misuse and dependence, particularly outside of medical supervision. Our structured treatment approach, careful screening, physician oversight, and follow-up care are designed to minimize these risks.
  • Can I continue taking my current medications?
    It depends on which medications you take. Some may affect how ketamine works or increase certain risks when combined with it. We review your medications and supplements before treatment and let you know if any changes are needed. Never stop or change a prescribed medication without guidance from your healthcare provider.
  • What does a ketamine session feel like?
    Ketamine can temporarily change how you experience your body, thoughts, emotions, and surroundings. Some patients describe relaxation, altered perception, a deeper inward focus, or a sense of mental flexibility. These effects are temporary, and our team remains nearby throughout the session.
  • Can I drive after my ketamine treatment?
    No. Ketamine can temporarily affect alertness, coordination, judgment, and reaction time. You should arrange for someone else to drive you home and follow our post-treatment instructions. Driving and other activities requiring full attention should be avoided until the effects have completely resolved.
  • How long does a ketamine treatment plan last, and how many sessions will I need?
    Treatment plans vary based on your symptoms, goals, and response to treatment. Some clinical protocols use an initial series of approximately four to six treatments over several weeks, while other schedules may be appropriate depending on the treatment approach. Your progress is monitored throughout treatment and the plan can be adjusted as needed.
  • Why is integration therapy an important part of treatment?
    Ketamine can create a temporary window of increased mental flexibility, but what happens afterward is an important part of the process. Integration helps you make sense of your experience, identify meaningful insights, and connect them to everyday life. The goal is to turn the treatment experience into practical, lasting change.
  • How soon can I expect to notice results from ketamine therapy?
    Some people notice shifts in mood, perspective, or emotional relief within hours to days, while others experience changes more gradually. We look at both your immediate response and how improvements develop throughout the course of treatment.
  • How do group ketamine therapy sessions work?
    Our group sessions are offered on scheduled dates in a structured, supportive setting. Participants receive medically guided treatment alongside others with shared goals, creating opportunities for connection and reflection while providing a more accessible treatment option.
  • How is ketamine-assisted therapy different from traditional antidepressants or therapy?
    Traditional antidepressants typically work gradually and are taken regularly to maintain their effect. Ketamine works differently by temporarily increasing mental flexibility, which may make thoughts, emotions, and behaviors feel less fixed. Therapy and integration can help patients explore and apply these shifts in everyday life.

Ketamine Therapy: Research & News

  • Ketamine versus ECT for Nonpsychotic Treatment-Resistant Major Depression

    Ketamine demonstrated comparable efficacy to ECT for adults with nonpsychotic, treatment-resistant major depression, offering rapid symptom improvement and sustained quality-of-life gains over six months.

    Read the Study

  • Ketamine for the treatment of mental health and substance use disorders: comprehensive systematic review

    A systematic review found ketamine-assisted interventions provide rapid and sustained symptom relief for depression, anxiety, PTSD, and certain substance use disorders, highlighting its potential as an effective adjunct to conventional therapies.

    Read the Study

  • A Cohort-Based Case Report: The Impact of Ketamine-Assisted Therapy Embedded in a Community of Practice Framework for Healthcare Providers With PTSD and Depression

    Embedding ketamine-assisted therapy within a supportive community framework helped healthcare providers with PTSD and depression achieve meaningful reductions in symptoms and improved overall mental well-being over time.

    Read the Study

Real Stories. Real Transformation.

Health and wellness is priceless, and given the current state of our medical system, it's worth it to have a team of amazing medical professionals be available to help me on my health journey.

C. R.

I had an excellent experience with Premier Integrative & Cognitive Institute. Their team was professional, responsive, and clearly knowledgeable.

Rachel C.

This clinic is AMAZING!!! The idea behind brain health is soooo innovative! We need this sort of medicine allover. Lynn and her amazing team have done an excellent job preparing this business with all the perfect details.

Libby A.

Convenient Location, Parking & Comfortable Care Environment

Our clinic is designed for ease, privacy, and comfort from the moment you arrive. Patients benefit from convenient on-site parking, elevator access, and quiet, climate-controlled treatment spaces. Use the map to plan your visit and experience a setting built to support focused, uninterrupted care.